Status:

RECRUITING

IDENTIFICATION OF PROGNOSTIC AND PREDICTIVE BIOMARKERS IN INFLAMMATORY BOWEL DISEASE

Lead Sponsor:

Central Hospital, Nancy, France

Conditions:

Inflammatory Bowel Diseases

Crohn Disease

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Interventional study of a group of patients with an inflammatory bowel disease (IBD; Crohn's disease (CD) or ulcerative colitis (UC)) to identify predictive and prognostic biomarkers of natural histor...

Detailed Description

Percentage of primary responders who haven't lost response to biotherapies during follow-up (anti-TNF, ustekinumab, vedolizumab). Response to treatment will be evaluated using objective criteria for ...

Eligibility Criteria

Inclusion

  • Age\>=18 years
  • Patients with an established diagnosis of CD or UC (clinical, biological, radiological, endoscopic or histologic criteria)
  • Patients \>=45 kg
  • Affiliated member of the Social Security system

Exclusion

  • Patients with an undetermined colitis
  • Patients with a non established diagnosis of CD
  • Women of childbearing age without a method of contraception
  • Persons covered by articles L. 1121-5, L. 1121-7 and L1121-8 of the Public Health Code
  • Pregnant women, breastfeeding women
  • \-- Age \< 18 years
  • Persons under legal protection
  • Person who does not have the capacity to consent
  • Persons under the age of 18 years who are deprived of their liberty by decision of a judicial or administrative authority (articles L. 3212-1 and L. 3213-1).

Key Trial Info

Start Date :

December 10 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 10 2034

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT03809728

Start Date

December 10 2019

End Date

December 10 2034

Last Update

February 7 2024

Active Locations (1)

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1

CHRU Nancy

Vandœuvre-lès-Nancy, France, 54510