Status:

UNKNOWN

Cryoballoon vs. Rhythmia Guided Ablation for Recurrent AFib

Lead Sponsor:

Valley Health System

Conditions:

Atrial Fibrillation

Eligibility:

All Genders

18-100 years

Phase:

NA

Brief Summary

The purpose of this research is to evaluate whether cryoballoon ablation vs. radiofrequency ablation guided by high-fidelity mapping (Rhythmia) is the best treatment strategy to perform repeat ablatio...

Detailed Description

The study is a randomized, prospective multicenter pilot study to assess the utility and efficacy of high-density mapping with the Rhythmia mapping system to guide PV re-isolation in subjects with rec...

Eligibility Criteria

Inclusion

  • Individuals with paroxysmal or persistent AF undergoing repeat AF ablation as per recent HRS guidelines and standard practice;
  • Individuals in whom the initial ablation approach was cryoballoon PVI at the enrolling institution more than 3 month or more prior to the anticipated repeat ablation;
  • Age ≥ 18 years.

Exclusion

  • Individuals with recurrent AF who previously underwent RF-based PVI;
  • Individuals with known contraindications to ablation including permanent atrial fibrillation or intolerance of anticoagulation;
  • Individuals unable or not willing to complete follow-up visits and examination for the duration of the study;
  • Individuals without access to smartphone or tablet compatible with the monitoring system;
  • Prior valve surgery or surgical AF ablation;
  • Individuals with mental or physical limitations precluding informed consent;
  • Individuals currently enrolled in another investigational study or registry;
  • Women of childbearing potential who are, or plan to become, pregnant during the time of the study.

Key Trial Info

Start Date :

November 27 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 1 2023

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT03811795

Start Date

November 27 2018

End Date

November 1 2023

Last Update

March 30 2021

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Iowa Heart Center

West Des Moines, Iowa, United States, 50266

2

The Valley Hospital

Paramus, New Jersey, United States, 07652

3

Peace Health

Springfield, Oregon, United States, 97477