Status:

UNKNOWN

Investigation of the Strategy of Preventing Post-operative Opioid-induced Hyperalgesia

Lead Sponsor:

Tri-Service General Hospital

Conditions:

Opioid-Induced Disorders

Eligibility:

FEMALE

20-80 years

Phase:

PHASE4

Brief Summary

The concept of Enhanced Recovery After Surgery(ERAS) has been prevalent in recent years. In the ERAS guideline, short-acting anesthetics, instead of long-acting opioid anesthetics, were recommended du...

Detailed Description

1. After obtaining informed consent, patients will be randomized into two groups. 2. All patients receive remifentanil-propofol based TIVA and Bispectral index (BIS) monitor during breast surgery. In ...

Eligibility Criteria

Inclusion

  • Subject's ASA (American Society of Anesthesiologists) Physical Status Classification: I (A normal healthy patient)\~III(A patient with severe systemic disease)
  • Subject has breast cancer and scheduled for breast surgery using total-intravenous anesthesia(TIVA)

Exclusion

  • Subject's ASA (American Society of Anesthesiologists) Physical Status Classification \>3
  • Subject doesn't receive total-intravenous anesthesia(TIVA) during surgery
  • Subject has psychiatric disease
  • allergic to opioid or propofol
  • History of alcoholism
  • History of drug abuse

Key Trial Info

Start Date :

January 11 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2019

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT03812003

Start Date

January 11 2019

End Date

December 31 2019

Last Update

January 22 2019

Active Locations (1)

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1

Tri-Service General Hospital

Taipei, Taiwan, 114