Status:

RECRUITING

Neuropsychological Assessment of Children and Adolescents With Turner Syndrome

Lead Sponsor:

University Hospital, Angers

Conditions:

Turner Syndrome

Isolated Growth Hormone Deficiency

Eligibility:

FEMALE

7-16 years

Brief Summary

Turner syndrome (TS) is a rare chromosomal disorder characterized by partial or complete loss of one of the X chromosomes that affects about one in every 2000 female babies born. These young patients ...

Detailed Description

Cross-sectional study (2 groups : Turner syndrome, isolated growth hormone deficiency), not randomized, controlled, associating several specialized centers in endocrine diseases. The pediatric endocr...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA
  • Turner syndrome group :
  • girls with diagnosed Turner syndrome.
  • Isolated GHD group :
  • girls with diagnosed isolated growth hormone deficiency
  • All participants :
  • age between 7 years to 16 years and 11 months.
  • informed consent signed by the participant and her parents (or her legal representatives)
  • being registered in the national social security system
  • EXCLUSION CRITERIA :
  • Turner syndrome group :
  • patients with chronic pathology other than Turner syndrome.
  • karyotype : part of a Y chromosome and r(X) cases.
  • medical treatment other than those usually prescribed in patients with Turner syndrome.
  • Isolated GHD group :
  • patients with chronic pathology other than isolated growth hormone deficiency.
  • medical treatment other than those usually prescribed in patients with isolated growth hormone deficiency.
  • All participants :
  • diagnosed intellectual disability (IQ\<70) or intellectual giftedness
  • history of acquired brain injury
  • sensory disturbances (auditory or visual) incompatible with the achievement of neuropsychological tasks.
  • insufficient French language proficiency

Exclusion

    Key Trial Info

    Start Date :

    September 5 2019

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 5 2025

    Estimated Enrollment :

    70 Patients enrolled

    Trial Details

    Trial ID

    NCT03812913

    Start Date

    September 5 2019

    End Date

    December 5 2025

    Last Update

    December 30 2024

    Active Locations (3)

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    Page 1 of 1 (3 locations)

    1

    CHU Rennes

    Rennes, Ile Et Vilaine, France, 35056

    2

    CHU Nantes

    Nantes, Loire Atlantique, France, 44300

    3

    CHU Angers

    Angers, Maine Et Loire, France, 49933