Status:
COMPLETED
The Effects of Sedatives on Tobacco Use Disorder
Lead Sponsor:
Wake Forest University Health Sciences
Conditions:
Tobacco Use Disorder
Eligibility:
All Genders
18-55 years
Phase:
PHASE1
PHASE2
Brief Summary
This proposal will obtain preliminary data on the effect of a single sub-anesthetic dose of a sedative on cigarette craving and smoking behavior as well as measuring tolerability and acceptability.
Eligibility Criteria
Inclusion
- smoke at least 5 cigarettes per day
- smoked at least 2 years
- negative urine drug screen for psychoactive drugs and negative breath alcohol concentration
- live in Little Rock AR or surrounding area
Exclusion
- unstable or stable medical condition that would interact with study medication or participation
- serious head trauma or neurological disorder
- hypertension, abnormal ECG or metabolic blood results
- meet criteria for psychosis, schizophrenia, major depressive disorder, or bipolar disorder
- use of psychoactive drugs or medications
- BMI \> 40
- among women, pregnancy or breastfeeding
Key Trial Info
Start Date :
June 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 31 2021
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03813121
Start Date
June 1 2019
End Date
August 31 2021
Last Update
October 6 2022
Active Locations (1)
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1
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States, 72205