Status:
COMPLETED
Personalized tDCS in Elderly Fallers Study
Lead Sponsor:
Hebrew SeniorLife
Conditions:
Accidental Falls
Aging
Eligibility:
All Genders
60-100 years
Phase:
NA
Brief Summary
The objective of this study is to determine if a four-week, 20-session intervention of personalized transcranial direct current stimulation (tDCS), as compared to sham intervention, improves dual task...
Detailed Description
In older adults, falls are costly, consequential and correlated with both physical and cognitive decline. Most falls occur when standing or walking. Many activities require people to stand or walk whi...
Eligibility Criteria
Inclusion
- Men and women aged 60 or older
- Self-report of mobility and balance problems
- Self-report of fear of falling defined by a "yes" answer to the yes-or-no question "Is the participant worried about falling in the future?"
- Trail Making Test (TMT) Part B time below 75th percentile of age-and education-based norms
- A score of 10 or below on the Short Physical Performance Battery
Exclusion
- Inability to stand or walk unassisted for 60 seconds
- Hospitalization within the past three months due to acute illness, or as the result of a musculoskeletal injury significantly affecting gait or balance
- Any unstable medical condition
- a diagnosis of a gait disorder, Parkinson's disease, Alzheimer's disease or dementia, multiple sclerosis, previous stroke or other neurodegenerative disorder
- Chronic vertigo
- Myocardial infarction within the past 6 months
- Active cancer for which chemo-/radiation therapy is being received
- Psychiatric co-morbidity including major depressive disorder, schizophrenia or psychosis
- Chronic use of any sedating medications (sedatives, anti-psychotics, hypnotics, anti-depressants) or change in medication within the previous month
- Legal blindness
- Contraindications to MRI or tDCS, including reported seizure within the past two years, use of neuro-active drugs, the risk of metal objects anywhere in the body, self-reported presence of specific implanted medical devices (e.g., deep brain stimulator, medication infusion pump, cochlear implant, pacemaker, etc.), or the presence of any active dermatological condition, such as eczema, on the scalp
- A score below 22 on the Telephone Interview of Cognitive Status (TICS)
- Mild or severe dementia defined by a Clinical Dementia Rating (CDR) score of one or greater
Key Trial Info
Start Date :
July 8 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2025
Estimated Enrollment :
118 Patients enrolled
Trial Details
Trial ID
NCT03814304
Start Date
July 8 2019
End Date
July 31 2025
Last Update
August 28 2025
Active Locations (1)
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1
Hebrew Rehabilitation Center
Roslindale, Massachusetts, United States, 02131