Status:

UNKNOWN

Surgical Treatment of Periimplantitis in Patients With Risk Factors

Lead Sponsor:

Luiz Antonio Pugliesi Alves de Lima

Conditions:

Peri-Implantitis

Type 2 Diabetes Mellitus

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

This study evaluates clinical and radiographic parameters among riks factor groups in patients with periimplantitis. This study will also treat and evaluate the patients response before and after surg...

Detailed Description

Periimplantitis (PI) is an inflammatory process that results in tissue attachment bone loss around the implant. Periodontal disease, smoke habit and type 2diabetes mellitus have been recognized as pot...

Eligibility Criteria

Inclusion

  • Implants diagnosed with peri-implantitis with boné defects; Probing depth ≥ 4mm; Positive Bleeding on Probing and Suppuration score; Radiographic Bone Loss ≥ 3mm; Generalized Chronic Periodontitis (Armitage, 1999); Heavy Smokers (\> 10 cigarets per day); Type 2 Diabetes Mellitus tipo 2 (ADA, 2005) with HbA1c between 6.5% and 7.5%

Exclusion

  • Complete Edentulism; Mucosal disease; Alcohol abuse; Systemic disease except type 2 Diabetes Mellitus, that might interfere in periimplantitis progression; Medication intake: anticoagulants, antineoplasics, contraceptives, bisphosphonates and antidepressives; Medication intake in the last 6 months: antibiotics; Medication intake in the last 3 months: antiinflammatories; Aggressive Periodontitis and Anaphylactic shock history; Periodontal treatment in the last 6 months before the baseline; Periodontal Pockets \> 7mm; Light Smokers (\< 10 cigarets/day); Implant Mobility.

Key Trial Info

Start Date :

May 28 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 28 2020

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT03814434

Start Date

May 28 2018

End Date

January 28 2020

Last Update

March 11 2019

Active Locations (1)

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1

Faculdade de Odontologia Universidade de Sao Paulo

São Paulo, São Paulo, Brazil