Status:
TERMINATED
Carry-over Effects of Repetitively Applied Transcutaneous Spinal Cord Stimulation on Spasticity
Lead Sponsor:
Swiss Paraplegic Research, Nottwil
Collaborating Sponsors:
Medical University of Vienna
Conditions:
Spinal Cord Injuries
Spasticity, Muscle
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Spinal cord injury is a devastating condition, causing substantial impairment of vital body functions caudal to the lesion. A major cause of disability stems from spasticity, a common secondary sequel...
Eligibility Criteria
Inclusion
- motor and sensory incomplete spinal cord injury classified as grade C or D on the American Spinal Injury Association Impairment Scale
- neurological level of spinal cord injury: third cervical to tenth thoracic segment
- chronic condition (≥ 12 months post-spinal cord injury)
- preserved segmental and cutaneo-muscular reflexes in the lower limbs
- able to be verticalized for 6 minutes (with walking aids)
- preserved joint mobility, no musculoskeletal diseases
- spasticity (with/without antispasticity medication)
- stable antispasmodic medication one month prior to as well as during study participation
Exclusion
- neuromuscular diseases, e.g., amyotrophic lateral sclerosis (ALS), Parkinson's disease, Guillain-Barré syndrome, muscular dystrophy
- dermatological issues at the stimulation site
- acute urinary tract infection at study entry
- active implants (e.g., cardiac pacemaker, drug pump)
- passive implants between the ninth thoracic level and the first lumbal level (e.g. metal screws/plates for surgical stabilization of spinal fractures)
- malignant diseases
- heart insufficiency
- potential pregnancy (pregnancy test to be conducted as part of the first evaluation)
Key Trial Info
Start Date :
January 7 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 10 2021
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT03815721
Start Date
January 7 2019
End Date
May 10 2021
Last Update
November 26 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Swiss Paraplegic Centre
Nottwil, Canton of Lucerne, Switzerland, 6207