Status:

UNKNOWN

Cerebrovascular Effects of the Use of Alpha-stat or pH-stat Management of Cardiopulmonary Bypass

Lead Sponsor:

Szeged University

Collaborating Sponsors:

GINOP

Hungarian Basic Research Council

Conditions:

Diabetes Mellitus

Cardiac Surgical Procedures

Eligibility:

All Genders

18-80 years

Brief Summary

Type 2 diabetes mellitus (T2DM) poses a significant burden on the patients and the health care system. The increasing number of surgery performed in elderly population results in an increased number o...

Detailed Description

One hour before the surgery, patients are premedicated with lorazepam (per os, 2.5 mg). Induction of anaesthesia is achieved by iv midazolam (30 μg/kg), sufentanyl (0.4-0.5 μg/kg), and propofol (0.3-0...

Eligibility Criteria

Inclusion

  • Patients undergoing cardiac surgery with or without diabetes mellitus
  • age between 18-80 years

Exclusion

  • patients older than 80 years of age
  • poor ejection fraction (\<40%)
  • unilateral internal carotid stenosis (\>75%)
  • medical history of smoking
  • medical history of chronic obstructive pulmonary disease
  • medical history of stroke

Key Trial Info

Start Date :

February 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 1 2020

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT03816280

Start Date

February 1 2019

End Date

July 1 2020

Last Update

May 16 2019

Active Locations (1)

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1

Cardiology Centre Cardiac Surgical Unit and Second Department of Internal Medicine, University of Szeged

Szeged, Csongrád megye, Hungary, 6725