Status:
COMPLETED
Diaphragmatic Breathing and Heart Rate Variability Training for Improving Hypertension in Fragile X Associated Tremor/Ataxia
Lead Sponsor:
University of California, Davis
Collaborating Sponsors:
UC Davis MIND Institute
UC Davis, Mini-Grant Geriatrics
Conditions:
Hypertension
FXTAS
Eligibility:
All Genders
50-90 years
Phase:
PHASE3
Brief Summary
To study whether heart rate variability training and respiratory coherence can improve hypertension in individuals with FXTAS. All patients will receive HRV biofeedback training for 20 sessions. Our ...
Detailed Description
Fragile X-associated tremor ataxia syndrome (FXTAS) is a late onset neurodegenerative disease that affects carriers of the fragile X premutation. This project proposes the evaluation of an innovative ...
Eligibility Criteria
Inclusion
- Males and females between the ages of 50-90 with a molecular documentation of a fragile X premutation, diagnosed with FXTAS.
- stable current pharmacological treatment regimen for at least 4 weeks.
- English speaking (the intervention is currently only available in English)
- Clinically significant hypertension.
- Normal or corrected to normal vision and hearing.
Exclusion
- Significant medical and behavioral problems that would interfere with the study (e.g. not being able to sit and play a computer game for 10 minutes)
- Participants who plan to initiate or change pharmacologic or non-pharmacologic interventions during the course of the study
- Individual is non-verbal (has no spoken language)
- English is not the primary language.
- Clinically critical Hypertension that requires medical attention
Key Trial Info
Start Date :
May 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 13 2019
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03816540
Start Date
May 1 2018
End Date
March 13 2019
Last Update
October 22 2019
Active Locations (1)
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1
University of California, Davis, MIND Institute
Sacramento, California, United States, 95817