Status:
COMPLETED
The Dose Response of Calcium Co-ingested With Protein on GLP-1 Concentrations
Lead Sponsor:
University of Bath
Collaborating Sponsors:
Arla Foods
Conditions:
GLP-1 Concentration
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Hormones that are produced by our stomach and intestines play a role in regulating our appetite and health. One of the most important hormones is called GLP-1. The food we eat influences the release o...
Detailed Description
Recent work at the University of Bath has shown that when ingested with 50 g whey protein hydrolysate, Capolac® (milk minerals high in calcium) potently stimulates availability of the important hormon...
Eligibility Criteria
Inclusion
- Body mass index 25.0-34.9 kg∙m-2
- Age 18-65 years
- Able and willing to provide informed consent and safely comply with study procedures
- Females to maintain record of regular menstrual cycle phase or contraceptive use
- No anticipated changes in diet/physical activity during the study (e.g. holidays or diet plans)
Exclusion
- Allergies or adverse reactions to calcium or milk proteins.
- Contradictions to a high intake of calcium e.g. history of kidney stones
- Any reported condition or behaviour deemed either to pose undue personal risk to the participant or introduce bias
- Any diagnosed metabolic disease (e.g. type 1 or type 2 diabetes)
- Any reported use of substances which may pose undue personal risk to the participants or introduce bias into the experiment
- Lifestyle not conforming to standard sleep-wake cycle (e.g. shift worker)
- Any reported recent (\<6 months) change in body mass (± 3%)
Key Trial Info
Start Date :
February 2 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 31 2021
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT03819972
Start Date
February 2 2019
End Date
March 31 2021
Last Update
April 28 2021
Active Locations (1)
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1
Department for Health, University of Bath
Bath, Somerset, United Kingdom, BA2 7AY