Status:

COMPLETED

Incisional Negative Pressure Wound Therapy in Patients Undergoing Spine Surgery

Lead Sponsor:

Nova Scotia Health Authority

Conditions:

Surgical Site Infection

Eligibility:

All Genders

17+ years

Phase:

NA

Brief Summary

Introduction: Posterior post-operative spine wounds involving surgery at multiple levels are known to have higher rates of wound complications relative to other areas of the body. Instrumentation, rep...

Detailed Description

Patients with surgical site infection (SSI) of the spine have higher morbidity and mortality and higher costs of care. Hospital length of stay has been shown to be significantly longer, and readmissio...

Eligibility Criteria

Inclusion

  • Capable of and agree to consent to randomization
  • Require spine surgery with a posterior midline incision that involves the thoracic, lumbar and/or sacral spine
  • Be one of the following clinical presentation groups:
  • Metastatic Tumor of the Thoracic or Lumbar spine (T1-S5), requiring instrumentation and decompression, with or without pre-operative site radiation
  • Revisions Surgery requiring additional instrumentation or revision instrumentation, for thoracolumbar degeneration or deformity (T1-S1), index surgery \>6 months prior
  • Acute Traumatic Thoracolumbar (T1-L5) fracture(s) with neurological deficit (AIS A-C), requiring instrumentation and decompression

Exclusion

  • Initially:
  • Undergoing percutaneous surgery
  • Active Surgical Site infection or Primary Spinal Column infection or Distant Site Infection (urinary tract, respiratory tract, etc.)
  • Subsequently:
  • Failure to complete the 6-week clinical follow-up (Loss to Follow Up)
  • Second surgery, at the same anatomical site, required during study time period (six weeks), for causes other than primary (SSI) or secondary (Dehiscence, Seroma) study endpoints.

Key Trial Info

Start Date :

July 15 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 12 2020

Estimated Enrollment :

2 Patients enrolled

Trial Details

Trial ID

NCT03820219

Start Date

July 15 2019

End Date

December 12 2020

Last Update

February 2 2023

Active Locations (1)

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1

Nova Scotia Health

Halifax, Nova Scotia (NS), Canada, B3L 4P1