Status:
TERMINATED
Transcranial Magnetic Stimulation (rTMS) as a Tool to Decrease Pain and Improve Functioning
Lead Sponsor:
VA Office of Research and Development
Conditions:
Opioid Use Disorder
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Despite the availability of opioid replacement therapies, many opioid use disordered Veterans are not able to remain abstinent. Repetitive Transcranial Magnetic Stimulation (rTMS) is a non-invasive ne...
Detailed Description
Opioid use disorders (OUDs) are common among Veterans. Despite the availability of opioid replacement therapies, many individuals continue to abuse opioids and relapse rates remain high. Veterans are ...
Eligibility Criteria
Inclusion
- Participants must be able to provide informed consent and function at an intellectual level sufficient to allow accurate completion of all assessment instruments.
- Participants must meet moderate to severe DSM-5 criteria for OUD. While individuals may also meet criteria for use disorders of other substances (with the exception of alcohol or benzodiazepines), they must identify opioids as their primary substance of abuse.
- Participants must report chronic pain for at least the past three months and have a Brief Pain Inventory score.
- Participants must be receiving treatment through the STAR program.
Exclusion
- Participants who are pregnant.
- Participants with a history of/or current psychotic disorder.
- Participants with a history of dementia or other cognitive impairment.
- Participants with active suicidal ideation, or a suicide attempt within the past 90 days will be excluded.
- Participants with contraindications to receiving rTMS (including a history of seizures, or any implanted metal above the neck).
- Those with unstable general medical conditions.
- Those who are currently using naltrexone or tramadol.
- Those with current alcohol or benzodiazepine use disorders due to increased risk of seizure.
Key Trial Info
Start Date :
October 11 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2021
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT03821337
Start Date
October 11 2019
End Date
December 31 2021
Last Update
December 21 2022
Active Locations (1)
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1
Ralph H. Johnson VA Medical Center, Charleston, SC
Charleston, South Carolina, United States, 29401-5799