Status:
RECRUITING
Bright Light Exposure in Surgical Patients
Lead Sponsor:
University of Colorado, Denver
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Myocardial Ischemia
Critical Illness
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
1. Elucidate the influence of intense light therapy pretreatment in patients undergoing cardiac surgery. We hypothesize that intense light exposure is associated with the peripheral stabilization of P...
Detailed Description
PER2 transcript and protein levels in patients undergoing cardiac surgery following intense light therapy utilizing blood samples, buccal swaps and right atrial myocardium. In addition, we will examin...
Eligibility Criteria
Inclusion
- Patients undergoing primary sternotomy cardiac surgery
- Subjects in the range of 18 - 90 years old .
- Patient need to be in sinus rhythm at the time of surgery.
Exclusion
- patients \<18 or \>90 years old
- participation in other clinical trials within the previous 30 days
- pregnancy
- neurological conditions that could impair weaning from ventilator support
- significant CNS disorders or comorbid irreversible conditions with a six-month mortality rate more than 50 percent
- prisoners, or subjects with altered capabilities to make decision will be enrolled
- medical history of type 2 diabetes
- patients with atrial fibrillation or use of class III anti-arhythmic drug
- patients with a left ventricle ejection fraction \< 40%
- patient in emergency condition
Key Trial Info
Start Date :
July 12 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2026
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT03822949
Start Date
July 12 2019
End Date
July 1 2026
Last Update
May 14 2025
Active Locations (1)
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1
University of Colorado Denver | Anschutz Medical Campus
Denver, Colorado, United States, 80220-3706