Status:
UNKNOWN
Lidocaine and Perioperative Cytokine Levels in Blood and Cerebrospinal Fluid in Cerebral Aneurysm Patients
Lead Sponsor:
Clinical Hospital Centre Zagreb
Conditions:
Aneurysm, Cerebral
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Cerebral aneurysm surgery has significant mortality and morbidity rate. Inflammation plays a key role in the pathogenesis of intracranial aneurysms, their rupture, subarachnoid haemorrhage and neurolo...
Eligibility Criteria
Inclusion
- ASA ( American Society of Anesthesiologists) grading status I-III,
- scheduled for cerebral aneurysm surgery under general anesthesia,
- signed informed consent for participating in the research.
Exclusion
- poorly controlled chronic or acute cardiovascular, respiratory or autoimmune disease,
- acute infectious disease,
- renal or hepatic insufficiency,
- preoperative Glasgow Coma Scale score lower than 15,
- allergic reaction to any of the medications in protocol,
- pregnancy
- refusal to participate in the research.
Key Trial Info
Start Date :
March 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2021
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03823482
Start Date
March 1 2019
End Date
December 1 2021
Last Update
November 12 2020
Active Locations (1)
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1
UHCZagreb
Zagreb, Croatia, 10000