Status:
COMPLETED
'Fitness To Fly' Tests In Children With Type II Respiratory Failure
Lead Sponsor:
Great Ormond Street Hospital for Children NHS Foundation Trust
Collaborating Sponsors:
University College, London
Conditions:
Neuromuscular Diseases
Central Hypoventilation
Eligibility:
All Genders
Up to 18 years
Phase:
NA
Brief Summary
The conventional hypoxic challenge test might not predict 'fitness-to-fly' equally well in all patients. Patients at risk of hypercapnia with supplemental oxygen are not well studied. Th investigators...
Detailed Description
This study will assess feasibility of pulse oximetry (SpO2), end tidal carbon dioxide (ETCO2) and transcutaneous carbon dioxide partial pressure (TcCO2) measurement during a modified Hypoxic challenge...
Eligibility Criteria
Inclusion
- ≤18 years
- Neuromuscular weakness or central hypoventilation
- Established nocturnal or intermittent daytime ventilatory support
Exclusion
- Unable to sit in the plethysmograph
- Cardiac anomaly with right-to-left shunt
Key Trial Info
Start Date :
February 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 31 2021
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03824223
Start Date
February 1 2019
End Date
August 31 2021
Last Update
December 8 2021
Active Locations (1)
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1
Great Ormond Street Hospital for Children NHS Foundation Trust
London, United Kingdom, WC1N 3JH