Status:

TERMINATED

Effect of Perioperative Intravenous Lidocaine Infusion in Robotic-Assisted Urologic Surgery

Lead Sponsor:

University of Missouri-Columbia

Conditions:

Kidney Cancer

Prostate Cancer

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Controlling pain is fundamental during and after surgical procedures. This study examines pain associated with robotic assisted surgery on prostate cancer or a kidney mass. In recent years, the risk o...

Detailed Description

In recent years, the risk of opioids in the post-operative period has gained interest due to the growing epidemic of addiction, dependence, and overdose. The rate of drug overdose secondary to opioids...

Eligibility Criteria

Inclusion

  • Undergoing robotic assisted prostatectomy or robotic assisted partial nephrectomy at University of Missouri Hospital for prostate cancer or kidney mass
  • Age ≥ 18 years
  • ASA I-III

Exclusion

  • Inability to obtain written informed consent
  • Allergy to lidocaine or other amide local anesthetics
  • Atrioventricular conduction blocks
  • CV instability and concomitant use of alpha agonists or beta blockers
  • Recent myocardial infarction (≤ 6 months ago)
  • Cardiac arrhythmia disorders
  • Stokes-Adams syndrome
  • Wolff-Parkinson-White syndrome
  • Seizure disorders
  • Liver failure or hepatic dysfunction
  • Significant renal disease with a serum creatinine ≥ 2 mg/dl
  • A family history of malignant hyperthermia
  • Current use of opioids or documented history of opioid abuse
  • Typically, have less than 3 bowel movement per week
  • Combined surgical cases that include robotic prostatectomy or robotic partial nephrectomy

Key Trial Info

Start Date :

February 26 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 26 2020

Estimated Enrollment :

21 Patients enrolled

Trial Details

Trial ID

NCT03824808

Start Date

February 26 2019

End Date

March 26 2020

Last Update

October 25 2023

Active Locations (1)

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1

University Hospital

Columbia, Missouri, United States, 65212