Status:
RECRUITING
Efficacy of Nitrous Oxide in OCD: Pilot Study
Lead Sponsor:
Stanford University
Collaborating Sponsors:
Brain & Behavior Research Foundation
Conditions:
Obsessive-Compulsive Disorder
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
This study investigates whether the commonly used and well-tolerated inhaled anesthetic nitrous oxide can rapidly improve symptoms of OCD.
Detailed Description
Obsessive-compulsive disorder (OCD) is a chronic and disabling disorder characterized by recurrent intrusive thoughts and associated compulsive behaviors that is estimated to affect more than 3 millio...
Eligibility Criteria
Inclusion
- Age 18-65
- Primary diagnosis of OCD
- Sufficient severity of OCD symptoms
- Ability to tolerate a treatment-free period
- Capacity to provide informed consent
Exclusion
- Psychiatric or medical conditions that make participation unsafe
- Pregnant or nursing females
- Concurrent use of any medications that might increase the risk of participation (e.g. drug interactions)
Key Trial Info
Start Date :
April 17 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2027
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT03826693
Start Date
April 17 2021
End Date
October 1 2027
Last Update
August 27 2025
Active Locations (1)
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1
Stanford University
Stanford, California, United States, 94304