Status:
COMPLETED
Poststroke Depression in Hemorrhagic Stroke
Lead Sponsor:
University of Washington
Conditions:
Stroke Hemorrhagic
Depression
Eligibility:
All Genders
18-85 years
Phase:
PHASE2
Brief Summary
A double-blinded placebo-controlled randomized trial to evaluate the effect of preventative treatment of depression in survivors of aneurysmal subarachnoid hemorrhage (aSAH), a type of stroke.
Detailed Description
Patients who suffered aneurysmal subarachnoid hemorrhage will be randomly assigned either an oral antidepressant or placebo and evaluated for the preventative treatment of depression and health-relate...
Eligibility Criteria
Inclusion
- Patients 18-85 years of age aged 18 years and older will be included.
- Patients admitted for subarachnoid hemorrhage from a ruptured cerebral aneurysm will be included.
- Only patients who provide informed consent will be included.
Exclusion
- Non-English speaking patients will be excluded.
- Patients currently receiving therapy for depression or related mental health diagnoses before admission will be excluded.
- Patients with medical contraindications to fluoxetine therapy will be excluded.
- Pregnant patients or patients considering pregnancy during the trial period at the time of consent will be excluded.
- Patients with active psychosis will be excluded.
- Patients who are incarcerated or in police custody will be excluded.
- Patients with a comorbidity or cognitive impairment (as determined by a recruiter-administered Montreal Cognitive Assessment; Patients scoring \>26 are considered of appropriate cognitive function for consent) that precludes informed consent and participation in the research interviews will be excluded.
Key Trial Info
Start Date :
March 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 7 2025
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT03826875
Start Date
March 1 2019
End Date
May 7 2025
Last Update
August 6 2025
Active Locations (1)
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1
Harborview Medical Center
Seattle, Washington, United States, 98104