Status:

COMPLETED

HMB Supplementation in Addition to Multicomponent Exercise in Old Adults

Lead Sponsor:

Universidad de Murcia

Conditions:

Aging

Frail Elderly Syndrome

Eligibility:

All Genders

70+ years

Phase:

NA

Brief Summary

Evidence supports the fact that multicomponent exercise and β-hydroxy-β-methylbutyrate (HMB) supplementation are, separately, effective in improving old adult's health and palliate functional metaboli...

Detailed Description

Evidence supports the fact that multicomponent exercise and β-hydroxy-β-methylbutyrate (HMB) supplementation are, separately, effective in improving old adult's health and palliate functional metaboli...

Eligibility Criteria

Inclusion

  • Men and women aged ≥70 years living in a nursing home
  • Be able to follow an active physical rehabilitation program
  • Be able to read and wright
  • Voluntary participation
  • Capable and willing to provide an informed consent

Exclusion

  • Acute heart attack (recent 3-6 months) or unstable angina
  • Uncontrolled atrial or ventricular arrhythmias
  • Aortic dissecting aneurysm
  • Severe aortic stenosis
  • Acute endocarditis / pericarditis
  • Uncontrolled high blood pressure (\>180/100 mmHg)
  • Acute thromboembolism
  • Acute or severe heart failure
  • Acute or severe respiratory failure
  • Uncontrolled postural hypotension
  • Uncontrolled acute decompensated diabetes mellitus or low blood sugar
  • A recent fracture in the last month.
  • Coincident participation in any intervention trial
  • HMB contraindication, intolerance, or allergy
  • Community-dwelling people
  • Have regularly performed exercise (\>20 minutes \>3 days/week) in the last 3 months
  • Malignant diseases (exceptions: basal or squamous-cell skin carcinoma or carcinoma in situ of the uterine cervix)
  • Revascularization within 1 year
  • Severe loss of vision, hearing, or communicative ability
  • Conditions preventing cooperation

Key Trial Info

Start Date :

March 30 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 30 2023

Estimated Enrollment :

104 Patients enrolled

Trial Details

Trial ID

NCT03827499

Start Date

March 30 2019

End Date

April 30 2023

Last Update

May 10 2023

Active Locations (1)

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1

Faculty of Sport Sciences

Murcia, San Javier, Spain, 30720