Status:
TERMINATED
Differentiate Children Septic and Inflammatory Arthritis by Comparative Analysis
Lead Sponsor:
University Hospital, Montpellier
Collaborating Sponsors:
Institut National de la Santé Et de la Recherche Médicale, France
Conditions:
Septic Arthritis
Inflammatory Arthritis
Eligibility:
All Genders
6-14 years
Brief Summary
The purpose is to found new biomarker that differentiate septic arthritis and Juvenile Idiopathic Arthritis in children. Synovial liquid and blood samples with proteomic, MiRNA searching, multiplex cy...
Detailed Description
This a multicentric prospective study that compares biological fluids as synovial liquid and blood samples to find biomarkers that could distinguish septic arthritis and juvenile idiopathic arthritis....
Eligibility Criteria
Inclusion
- Group A and group B:
- Subject of more than 6 months and under age 15 years,
- Presenting acute arthritis taken care in the University Hospitals of Montpellier, Nimes, Toulouse or Lyon, and requiring an articular puncture,
- Child benefiting from a social security system,
- Collection of the consent of the legal parents/representatives,
- Group C:
- Subject of more than 6 months and under age 15 include,
- Taken care in the University Hospital of Montpellier, and requiring a venous draining,
- Child benefiting from a social security system,
- Collection of the consent of the legal parents/representatives
Exclusion
- Group A and group B:
- Contraindication in an articular draining: platelet 50 000/mm3, pathologic hemostasis
- Treatment by biological therapy, corticoids or other immunosuppressant treatment in the month preceding the articular draining,
- antibiotic begun more than 24 hours before the inclusion.
- Group C:
- Patient achieves of an inflammatory chronic pathology
- Patient having presented an infectious episode in the previous 8 days
- Patients under immunosuppressor or anti-infective
Key Trial Info
Start Date :
February 4 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 29 2022
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03827759
Start Date
February 4 2019
End Date
July 29 2022
Last Update
June 22 2025
Active Locations (5)
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1
CHU Montpellier - Pediatric emergencies
Montpellier, Hérault, France, 34295
2
Hospices Civils de Lyon - pediatric rheumatology
Lyon, France, 69002
3
Hôpital Saint Joseph
Marseille, France, 13285
4
CHU Nîmes - Pediatrics
Nîmes, France, 30029