Status:
UNKNOWN
Individualized rTMS Protocol for Stroke Recovery
Lead Sponsor:
Chang Gung Memorial Hospital
Conditions:
Stroke
Eligibility:
All Genders
20-75 years
Phase:
NA
Brief Summary
This study aims to develop individualized therapeutic protocol to improve stroke recovery and fits the scheme of Mechanisms, biomarkers, and treatment strategies for stroke, aging, and Parkinson's dis...
Detailed Description
It has long been a challenge to promote the recovery after stroke. So far, rehabilitation has been the most evident way for this purpose, while pharmacological approaches have done very little. Howev...
Eligibility Criteria
Inclusion
- first-ever stroke
- in subacute stage (between 1-3 months after stroke onset)
- monohemispheric ischemic stroke
- able to follow the command of the shoulder flexion
- mild to moderate paresis in the upper limb (the motor arm score of National Institute of Health Stroke Scale (NIHSS) = 1 \& 2 out of 4, where 4 = no movement)
Exclusion
- being less than 20 years or over 75 years of age
- history of seizures or epileptiform discharges on electroencephalogram (EEG)
- pregnancy
- aphasia, apraxia, and concomitant neurological diseases or other severe medical diseases (e.g., sepsis, malignancy, hepatic or renal failure).
- having a pacemaker, an implanted medication pump, a metal plate in the skull, or metal objects inside the eye or skull (for example after brain surgery or a shrapnel wound)
- taking tricyclic antidepressants, neuroleptic agents and other drugs that lower the seizure threshold
- Insulin dependent diabetes
- Thyroid disease
Key Trial Info
Start Date :
April 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2019
Estimated Enrollment :
170 Patients enrolled
Trial Details
Trial ID
NCT03828435
Start Date
April 1 2016
End Date
December 1 2019
Last Update
February 4 2019
Active Locations (1)
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1
Ying-Zu Huang
Taoyuan District, Taiwan, 333