Status:

COMPLETED

Uterine Scratching in Intra-Uterine Insemination

Lead Sponsor:

Clinique Ovo

Conditions:

Infertility

Unexplained Infertility

Eligibility:

FEMALE

18-41 years

Phase:

NA

Brief Summary

This study will evaluate the potential benefits of uterine injury during the follicular phase of an intra-uterine insemination cycle on the rate of ongoing pregnancy during the first trimester ultraso...

Detailed Description

Infertility is defined as the absence of conception after a year of unprotected intercourse. In 10 to 30 % of patients, the cause of the infertility is unknown. An emerging practice in unexplained inf...

Eligibility Criteria

Inclusion

  • Unexplained infertility for over 12 months if under 35 years old or over 6 months if 35 years old and above.
  • At least one permeable tube on hysterosonography or hysterosalpingography within the last 2 years or vaginal delivery in the last 3 years.
  • Antral follicular count over 5.
  • Normal or mild male factor.
  • Normal uterine cavity.
  • An IUI prescription.

Exclusion

  • Polycystic ovary syndrome with irregular menstrual cycles over 45 days
  • Severe endometriosis
  • IUI with Donor sperm
  • Patient with invasive intra-uterine procedure in the last 3 months.
  • Contraindication to endometrial biopsy.

Key Trial Info

Start Date :

July 15 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 30 2024

Estimated Enrollment :

394 Patients enrolled

Trial Details

Trial ID

NCT03828786

Start Date

July 15 2018

End Date

March 30 2024

Last Update

March 20 2025

Active Locations (1)

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Clinique Ovo

Montreal, Quebec, Canada, H4P 2S4