Status:
COMPLETED
Effects of Oxytocin and Lorazepam on Fear-related Intra-amygdalar Activity
Lead Sponsor:
University Hospital, Bonn
Conditions:
Oxytocin, Lorazepam, Anti-Anxiety Agents, Physiological Effects of Drugs
Eligibility:
MALE
18-40 years
Phase:
PHASE1
Brief Summary
High-potency benzodiazepines have strong anxiolytic effects accompanied by significant adverse effects including impaired cognitive function, drowsiness, dizziness and impaired motoric abilities. Impo...
Eligibility Criteria
Inclusion
- healthy male volunteers
- right-handed
Exclusion
- Current or past psychiatric illness
- Current or past physical illness
- Psychoactive medication
- Sedative medication
- MRI contraindication (e.g. metal in body, claustrophobia)
Key Trial Info
Start Date :
March 3 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 16 2017
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT03829839
Start Date
March 3 2016
End Date
August 16 2017
Last Update
April 17 2019
Active Locations (1)
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1
Department of Psychiatry, University of Bonn
Bonn, Germany, 53105