Status:
ACTIVE_NOT_RECRUITING
PErsonalized Genomics for Prenatal Abnormalities Screening USing Maternal Blood
Lead Sponsor:
CHU de Quebec-Universite Laval
Collaborating Sponsors:
Genome Quebec
Genome British Columbia
Conditions:
Prenatal Disorder
Aneuploidy
Eligibility:
FEMALE
19+ years
Phase:
NA
Brief Summary
This project aims to provide high- quality evidence to inform decisions by health care organisations about using first-tier non-invasive prenatal screening (NIPS) to replace traditional screening test...
Detailed Description
There is some data on the performance of NIPS as a first tier screening test but our systematic review has shown that no trial comparing the effectiveness (utility) of 2nd-tier NIPS with that of first...
Eligibility Criteria
Inclusion
- Pregnant women 19 years or older wanting prenatal screening
- 10-13+6 wks determined by dating ultrasound or last menstrual period.
- Not intending to pursue self pay NIPT
Exclusion
- Known fetal anomaly at the time of recruitment
- Multiple gestation
- Known twin demise
- Planned CVS or amnio for known genetic condition.
Key Trial Info
Start Date :
January 13 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2025
Estimated Enrollment :
7849 Patients enrolled
Trial Details
Trial ID
NCT03831256
Start Date
January 13 2020
End Date
June 30 2025
Last Update
February 12 2025
Active Locations (6)
Enter a location and click search to find clinical trials sorted by distance.
1
Kelowna Regional Fertility Center
Kelowna, British Columbia, Canada, V1Y 1P2
2
Prince Rupert Regional Hospital
Prince Rupert, British Columbia, Canada, V8J 2A6
3
Children's & Women's Health Centre
Vancouver, British Columbia, Canada, V6H 3N1
4
CHU Ste-Justine
Montreal, Quebec, Canada, H3T 1C5