Status:
RECRUITING
Value of Analysing Under-utilised Leftover Tissue (VauLT)
Lead Sponsor:
Royal Marsden NHS Foundation Trust
Collaborating Sponsors:
Ventana Medical Systems
Conditions:
Oncology
Eligibility:
All Genders
18+ years
Brief Summary
Intratumour heterogeneity is well recognized in multiple cancer types and ultimately leads to therapeutic resistance. It also limits the ability of small samples to represent the whole tumour, having ...
Detailed Description
In order to establish the feasibility of homogenization as a potential companion diagnostic tool, our study aims to 1) evaluate how many surgical cases have left over tissue amenable to homogenization...
Eligibility Criteria
Inclusion
- Leftover formalin-fixed tissue (ie that would be otherwise discarded by histopathology) from cancer surgery.
- Tissues for Research consent has been provided.
- Patient age \>18yo.
- Minimum of 1 gram of residual tumour remaining in leftover surgical tissue
- Minimum of 1 gram of normal tissue present.
Exclusion
- Advanced Practitioner in histological dissection deems tumour sample to be inadequate.
- Leftover surgical tumour tissue greater than 20kg.
Key Trial Info
Start Date :
September 10 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2028
Estimated Enrollment :
800 Patients enrolled
Trial Details
Trial ID
NCT03832062
Start Date
September 10 2018
End Date
December 31 2028
Last Update
May 18 2025
Active Locations (1)
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1
Royal Marsden Hospital NHS Foundation Trust
London, United Kingdom, SW3 6JJ