Status:
COMPLETED
Non-invasive Ventilation vs Oxygen Therapy After Extubation Failure
Lead Sponsor:
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Conditions:
Respiratory Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Non-invasive mechanical ventilation (NIV) has not exhibited a reduction of reintubation after extubation failure compared to oxygen therapy. The reduction of reintubation with NIV versus oxygen therap...
Detailed Description
Patients. Medical and surgical patients admitted to intensive care unit with 18 years of age or older in weaning from their first episode of mechanical ventilation for more than 24 hours were included...
Eligibility Criteria
Inclusion
- Medical and surgical ICU patients with 18 years of age or older
- First episode of mechanical ventilation for more than 24 hours
Exclusion
- Structural neurological disorder
- Acute toxic-metabolic neurological encephalopathy with neurological deficit \[estimated by a Glasgow Coma Score (GCS) \<14 points\] at the time of weaning
- Neuromuscular disease
- Chronic obstructive pulmonary disease (COPD) receiving NIV
- Limitation of life support therapy during their admission
- Tracheostomized patients
- Spinal cord injuries
- Scheduled surgical procedure during the 48 hours following extubation
- Intensive care unit readmission
- Transfer to another centre
- Contraindication to non-invasive mechanical ventilation
Key Trial Info
Start Date :
March 29 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 4 2016
Estimated Enrollment :
77 Patients enrolled
Trial Details
Trial ID
NCT03832387
Start Date
March 29 2009
End Date
September 4 2016
Last Update
June 4 2019
Active Locations (1)
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1
Hospital General Universitari Castello
Castellon, Castello, Spain, 12004