Status:
RECRUITING
Oesophagectomy and Chest Wall and Respiratory Function
Lead Sponsor:
Imperial College London
Conditions:
Esophageal Cancer
Esophagectomy
Eligibility:
All Genders
18-90 years
Brief Summary
Open surgery for esophageal cancer commonly involves large incisions in the chest, associated with a high rate of pulmonary complications (30-50%). Minimally invasive approach through keyhole surgery ...
Detailed Description
The study population consists of 40 healthy volunteers who have not received upper gastrointestinal surgery and 60 patients treated with surgery more than one year ago (open approach). Chest wall move...
Eligibility Criteria
Inclusion
- Exposure group:
- Patients treated more than a year ago with oesophagectomy for oesophageal cancer, by an open approach.
- Patients able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study.
- Control group:
- Healthy volunteers with no underlying respiratory disease and no history of upper gastrointestinal surgery.
- Individuals able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study.
Exclusion
- Any participant who lacks capacity or is unable to provide informed consent.
- Any participant younger than 18 or older than 90 years of age.
- Any patient with evidence of cancer recurrence or on-going postoperative complication at more than one year following surgery for oesophageal cancer.
- Any pregnant participant.
- unable to or excluded from performing spirometry or respiratory muscle strength testing (non-invasive testing)
Key Trial Info
Start Date :
May 29 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 31 2025
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03835273
Start Date
May 29 2019
End Date
August 31 2025
Last Update
July 3 2025
Active Locations (1)
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1
Charing Cross Hospital
London, United Kingdom, W6 8RF