Status:

ACTIVE_NOT_RECRUITING

Titanium Zirconium (TiZr) Mini Implants

Lead Sponsor:

University of Bern

Conditions:

Dental Implants

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

H0: "Within the first year post-placement, four interforaminally placed, immediately loaded 2.4 mm narrow-diameter one-piece TiZr implants with miniaturized stud-type attachments show improved patient...

Eligibility Criteria

Inclusion

  • At patient level:
  • Written informed consent
  • Age ≥ 18 years
  • Sufficient complete dentures (Marxkors and Ferger, 1989) not older than 1 year
  • Patient is unsatisfied with mandibular denture to the degree that he/she seeks treatment
  • At site level:
  • Healed edentulous mandible (minimum 8 weeks since last extraction)
  • Minimal ridge dimensions 5.5 mm (width) by 12 mm (height) in the anterior (interforaminal) area, allowing the placement of 3.3 (endosseous diameter) by 10 mm (length) implants
  • Opposing dentition: complete denture on a edentulous maxilla
  • Physical status (PS) 1 and 2 (American Society of Anesthesiologists)

Exclusion

  • At patient level
  • Any physical or mental disorder that would interfere with the ability to perform adequate oral hygiene or the capability of providing written informed consent and compliance to the protocol
  • Any disorder that would interfere with wound healing or represent a contraindication for oral surgery such as, but not limited to, uncontrolled diabetes or conditions resulting in or requiring immunosuppression, radiation, chemotherapy, frequent use of antibiotics or antiresorptive medication such as bisphosphonates
  • Pregnancy or lactation
  • Heavy smoking habit with \> 20 cig/d
  • Severe bruxism or clenching habits, present oro-facial pain
  • At site level:
  • Ridge defects requiring staged bone augmentation procedures (simultaneous Guided Bone Regeneration (GBR) within the ridge contour allowed)

Key Trial Info

Start Date :

September 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2033

Estimated Enrollment :

72 Patients enrolled

Trial Details

Trial ID

NCT03837158

Start Date

September 1 2019

End Date

August 1 2033

Last Update

November 6 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Private Practice Dr. B. Wallkamm

Langenthal, Canton of Bern, Switzerland, 4900

2

University of Bern

Bern, Switzerland, 3010