Status:
UNKNOWN
Whole-Exome Sequencing (WES) of Intraductal Neoplasms of the Bile Duct (IPNB)
Lead Sponsor:
Fujian Provincial Hospital
Collaborating Sponsors:
Fujian Medical University Union Hospital
First Affiliated Hospital of Fujian Medical University
Conditions:
Bile Duct Neoplasms
Intraductal Papillary Mucinous Neoplasm
Eligibility:
All Genders
18-80 years
Brief Summary
Intraductal papillary neoplasm of the bile duct (IPNB) is a distinct type of biliary tumor characterised with delicate fibrovascular stalks (papillary of villous) covered at biliary epithelium. The ty...
Detailed Description
Using production-scale platform, this study will carry out whole exome sequencing from archival (FFPE) material to Identification and classification of significantly mutated genes, determine the somat...
Eligibility Criteria
Inclusion
- Clinical diagnosis of IPNBs
- ECOG Performance status of 0, 1, or 2
- Adequate liver function, bilirubin \< 1.5 times ULN, ALT or AST \< 2.5 times ULN
- Adequate renal function: creatinine \< 1.8
- Must be at least 18
Exclusion
- Diagnosis of hepatic mucinous cystadenoma (MCN)
- Complicated with other Malignancy
- Pregnancy
Key Trial Info
Start Date :
February 15 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2019
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03838913
Start Date
February 15 2019
End Date
December 31 2019
Last Update
February 12 2019
Active Locations (1)
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1
Yaodong Wang
Fuzhou, Fujian, China, 350001