Status:
UNKNOWN
Safety Observation on hESC Derived MSC Like Cell for the Meniscus Injury
Lead Sponsor:
Tongji Hospital
Collaborating Sponsors:
Chinese Academy of Sciences
Conditions:
Meniscus Injury
Eligibility:
All Genders
18-65 years
Phase:
PHASE1
Brief Summary
human embryonic stem cell derived mesenchymal stem cells like cell for the meniscus injury, and observe the safety of the cells for meniscus injury
Detailed Description
Three different dosage of human embryonic stem cell derived mesenchymal stem cells like for meniscus injury patients, and observe the safety of the cells for meniscus injury.
Eligibility Criteria
Inclusion
- Grade Ⅰ-Ⅱ meniscus injury of knee joint
- The patients who still have the pain of knee joint and/or limitation of the function after accepted 3 months of nonoperative treatment
Exclusion
- Recent history of lower limb fractures or intra-articular drug injection
- The patients who have meniscus injury of knee joint need the surgical repair
- The patients who have the severe coagulation disorders, cardiopulmonary failure and so on
- The women who are pregnant or nursing
- There are electronic implants such as pacemakers in the body
- The patients who are infected the HIV, the virus of hepatitis or syphilis
- The patients who are alcoholism or drug user
- The patients who have vestibular and balance disorders
- The patients with severe cognitive impairment who cannot follow instructions to complete the treatment
- The patients who don't sign the informed consent
- The patients who have tumor
- Immunodeficiency patients
- The patients who have congenital or acquired knee malformation
- Patients or researchers who are participating in other clinical trials believe that other reasons are not appropriate for clinical trials
Key Trial Info
Start Date :
January 4 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2020
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT03839238
Start Date
January 4 2019
End Date
September 30 2020
Last Update
February 15 2019
Active Locations (1)
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1
Tongji Hospital, Tongji Medical College of Science and Technology
Wuhan, Hubei, China, 430030