Status:
COMPLETED
Predict MDE Outcomes After MST
Lead Sponsor:
Shanghai Mental Health Center
Conditions:
Major Depressive Episode
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
This trial attempts to explore the treatment outcome of magnetic seizure therapy (MST) for major depressive episode. Half of the participants will receive MST, while the other half will receive electr...
Detailed Description
Magnetic seizure therapy (MST) is likely to be an alternative options to electroconvulsive therapy (ECT). Widespread stimulation of cortical and subcortical regions is inevitable for ECT since the su...
Eligibility Criteria
Inclusion
- DSM-5 diagnosis of major depressive episode;
- convulsive therapy clinically indicated, such as severe psychomotor excitement or retardation, attempts of suicide, being highly aggressive, pharmacotherapy intolerance, and ineffectiveness of antipsychotics;
- the HAMD-17 ≥ 24;
- informed consent in written form.
Exclusion
- primary diagnosis of other mental disorders;
- severe physical diseases, such as stroke, heart failure, liver failure, neoplasm, and immune deficiency;
- present with a laboratory abnormality that could impact on efficacy of treatments or safety of participants;
- failure to respond to an adequate trial of ECT lifetime;
- are pregnant or intend to get pregnant during the study;
- Unremovable metal implants.
- other conditions that investigators consider to be inappropriate to participate in this trial.
Key Trial Info
Start Date :
July 20 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 10 2023
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT03841019
Start Date
July 20 2020
End Date
May 10 2023
Last Update
October 31 2023
Active Locations (1)
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1
Shanghai Mental Health Center
Shanghai, Shanghai Municipality, China, 200030