Status:
COMPLETED
Non-Opioid Pramipexole and Pain
Lead Sponsor:
University of New Mexico
Conditions:
Chronic Pain
Eligibility:
All Genders
18+ years
Phase:
EARLY_PHASE1
Brief Summary
The long-term goal of this proposal is to identify non-opioid drugs that harness endogenous anti-inflammatory mechanisms resulting in the suppression of proinflammatory cytokines such as IL-1ß providi...
Detailed Description
The long-term goal of this proposal is to identify non-opioid drugs that harness endogenous anti-inflammatory mechanisms resulting in the suppression of proinflammatory cytokines such as IL-1ß providi...
Eligibility Criteria
Inclusion
- Nonmalignant chronic pain patients at University of New Mexico Pain Clinic, reporting suboptimal pain control, who state an interest to try something new to improve pain relief
- Pain score of 5 or greater (0-10 scale)
- Pain lasting more than 3 months
Exclusion
- Patients who do not speak English or Spanish
- Patients unable to consent
- Women who are not post-menopausal, or who have not undergone an oophorectomy/hysterectomy
- Patients who have chronic pulmonary, kidney or liver disease
- Patients with a body mass index (BMI) ≥35
- Patients with a cancer diagnosis within the last 2 years (except non-melanoma skin cancer)
- Patients who are currently lactating
- Patients with a history of orthostatic hypotension
- Patients diagnosed with a dissociative disorder
- Patients with Parkinson's disease, and/or currently taking dopamine agonist prescription medications
- Prisoners and other institutionalized individuals
Key Trial Info
Start Date :
May 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 15 2021
Estimated Enrollment :
13 Patients enrolled
Trial Details
Trial ID
NCT03842709
Start Date
May 1 2019
End Date
February 15 2021
Last Update
October 23 2024
Active Locations (1)
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1
University of New Mexico Hospital
Albuquerque, New Mexico, United States, 87131