Status:
UNKNOWN
Effect of Tiotropium on Airway Remodeling in Patients With Early Stage COPD Accessed by Optical Coherence Tomography
Lead Sponsor:
Guangzhou Institute of Respiratory Disease
Conditions:
Airway Remodeling
Eligibility:
All Genders
40-80 years
Phase:
NA
Brief Summary
The study aims to explore the effect of tiotropium on airway remodeling by using Endobronchial Optical Coherence Tomography (EB-OCT). We enrolled patients with GOLD I stage COPD. All the patients will...
Eligibility Criteria
Inclusion
- Key inclusion criteria
- Over 40 yrs; Male or female Diagnosed with COPD
- Pre-bronchodilator FEV1 ≥80% pred ;
- Patients must be able to perform all study related procedures
- Exclusion Criteria:
- Patients with other lung diseases (such as bronchiectasis, pneumothorax, pleural effusion, airway deformation, lung surgery, etc.).
- Patients have poor compliance and are unwilling to receive medication regularly.
- Other complications of bronchoscopy or intolerance of bronchoscopy procedure.
Exclusion
Key Trial Info
Start Date :
October 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2022
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03842839
Start Date
October 1 2018
End Date
December 1 2022
Last Update
September 29 2022
Active Locations (1)
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1
Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China, 510120