Status:
COMPLETED
Dose-dependent Effects of Oxytocin on the Amygdala and Reward System
Lead Sponsor:
University Hospital, Bonn
Conditions:
Healthy
Eligibility:
FEMALE
18-40 years
Phase:
PHASE1
Brief Summary
The purpose of this study is to determine whether effects of intranasal oxytocin on amygdala and reward system responses vary as a function of treatment dose in women in comparison to men.
Detailed Description
The objective of the present study is to determine whether intranasal oxytocin (IN-OXT) effects on blood oxygenation level-dependent functional magnetic resonance imaging (BOLD fMRI) in the amygdala a...
Eligibility Criteria
Inclusion
- Healthy female volunteers
- Right-handed
- Non-smoker
Exclusion
- Current psychiatric or physical illness
- Hormonal contraception
- Psychoactive medication
- MRI contraindication (e.g. metal in body, claustrophobia)
- Pregnancy
Key Trial Info
Start Date :
April 3 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2018
Estimated Enrollment :
92 Patients enrolled
Trial Details
Trial ID
NCT03846739
Start Date
April 3 2017
End Date
December 31 2018
Last Update
February 28 2019
Active Locations (1)
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1
Department of Psychiatry, University of Bonn
Bonn, Germany, 53105