Status:
COMPLETED
Dose Painting of Head and Neck Cancer
Lead Sponsor:
Oslo University Hospital
Conditions:
Head and Neck Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Dose-painting may increase the chance of cure at minimised radiation-induced toxicity in volumetric-arc radiotherapy (VMAT) for head and neck cancer. This trial (RADPAINT) investigates the safety of F...
Detailed Description
In this study, radiotherapy is planned using 18F-FDG PET/CT (18F-2-fluoro-2-deoxy-D-glucose fluorodeoxyglucose positron emission tomography) making one experimental "dose-painting by contours" SIB (si...
Eligibility Criteria
Inclusion
- Histologically or cytologically verified invasive squamous cell carcinoma of the head and neck region; Oral cavity, hypopharynx cancer, larynx cancer and HPV ((human papillomavirus) negative oropharyngeal cancer.
- Patients planned for standard curative treatment (radical radiotherapy with or without concomitant chemotherapy, with nimorazole hypoxic cell radiosensitizer)
- Planned treatment at the Oslo University Hospital
- Age \> 18 years
- WHO (World Health Organization) performance status 0-2
Exclusion
- TNM (primary tumor, regional nodes, metastasis) stage cT1 cN0-N1 cM0
- Glottic cancer cT1-T2 cN0 cM0
- HPV positive oropharyngeal carcinoma
- Cancer in the soft palate
- Diabetes mellitus
Key Trial Info
Start Date :
December 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 16 2022
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT03847480
Start Date
December 1 2018
End Date
December 16 2022
Last Update
February 21 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Oslo University Hospital
Oslo, Norway