Status:

COMPLETED

Validation of Peptest™ for the Detection of Reflux in Cough

Lead Sponsor:

Hull University Teaching Hospitals NHS Trust

Conditions:

Cough

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Chronic cough is a common presenting problem which has a significant impact on quality of life. Gastro-oesophageal reflux (GOR) is a common cause of chronic cough and reflux of stomach contents into t...

Eligibility Criteria

Inclusion

  • A negative score for airway reflux (HARQ score \<13).
  • Provision of informed consent.

Exclusion

  • Participants with a positive score for airway reflux (HARQ score \>13).
  • Chronic respiratory disease.
  • Acute gastro-respiratory illness at the time of the study.
  • Participants who will be physically unable to undergo sputum collection or cough induction.
  • Those who are unwilling to undergo cough challenge and induction of cough.
  • Smoking or consumption of food, caffeinated or carbonated beverages for 30 minutes prior to sample collection.

Key Trial Info

Start Date :

August 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2014

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03851393

Start Date

August 1 2014

End Date

October 1 2014

Last Update

July 15 2019

Active Locations (1)

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1

Hull Clinical Trials Unit, Respiratory academic department

Cottingham, Yorkshire, United Kingdom, HU16 5JQ