Status:

COMPLETED

Safety and Efficacy of Wendan Decoction in Acute Moderated to Severe Brain Injury

Lead Sponsor:

Taichung Tzu Chi Hospital

Conditions:

Acute Brain Injury

Eligibility:

All Genders

18-80 years

Phase:

PHASE2

PHASE3

Brief Summary

Efficacy and safety of Traditional Chinese Medicine (Wendan decoction) combined with conventional neurologic intensive care in patients with acute moderated to severe brain injury in early stage - A r...

Detailed Description

This study adopted a prospective, randomized controlled design. All eligible patients included in the study agreed to participated and signed the informed consent from and the study procedures were ap...

Eligibility Criteria

Inclusion

  • traumatic brain injury or spontaneously intracerebral hemorrhage within 14 days of onset;
  • an initial score of 3-12 points of GCS score;
  • adults between 18 to 80 years old;
  • and signed informed consent form.

Exclusion

  • after 14 days of onset;
  • a history of previous TBI or stroke;
  • intracranial aneurysm or arteriovenous malformation ruptured;
  • combination other major organ injury (heart, lung, intra-abdomen organ, pelvic fracture, major vessels);
  • other severe disease such as heart or kidney failure;
  • previous diagnosed cancer; and pregnant women.

Key Trial Info

Start Date :

June 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 31 2016

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT03851809

Start Date

June 1 2014

End Date

January 31 2016

Last Update

February 22 2019

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