Status:
COMPLETED
Blood Eosinophil Measurements in Patients With Chronic Obstructive Pulmonary Disease
Lead Sponsor:
Universitair Ziekenhuis Brussel
Collaborating Sponsors:
Vrije Universiteit Brussel
Conditions:
Chronic Obstructive Pulmonary Disease
Eligibility:
All Genders
18+ years
Brief Summary
This study will assess the within-day variation of blood eosinophils in patients with Chronic Obstructive Pulmonary disease (COPD) in stable state and determine if there is a correlation between the b...
Detailed Description
COPD is a heterogeneous disease, resulting in different phenotypes with varying clinical and pathophysiological characteristics. One of these pathophysiological features is chronic airway inflammation...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Patients willing and able to give informed consent for participation in the study.
- Age 18 years or older.
- Diagnosis of COPD according to GOLD (Global Initiative for Chronic Obstructive Lung Disease): post-bronchodilator Tiffeneau index \<0.7), in a stable state of the disease.
- A smoking history of \>10 pack-years
- Exclusion criteria:
- Clinical diagnosis of asthma.
- Use of systemic corticosteroids (oral, intravenous or infiltration) up to six weeks before inclusion.
- Pregnancy.
- A recent exacerbation of COPD (\<4 weeks).
Exclusion
Key Trial Info
Start Date :
March 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 28 2020
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT03853642
Start Date
March 1 2019
End Date
March 28 2020
Last Update
March 30 2020
Active Locations (1)
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1
Universiatir Ziekenhuis Brussel
Brussels, Belgium, 1090