Status:

UNKNOWN

NALDEBAIN for Postoperative Pain Management in Take Down of Anastomosis

Lead Sponsor:

China Medical University Hospital

Conditions:

Postoperative Pain

Eligibility:

All Genders

20-80 years

Phase:

PHASE4

Brief Summary

NALDEBAIN ER injection, invented by Taiwanese, launched in 2017, is a nalbuphine synthetic prodrug with oil-based solution to extend the release in human body by intramuscular injection. It was approv...

Detailed Description

This is an open-labeled, randomized clinical trial. After ICFs are signed, patients' medical history will be gained for checking if they are eligible for this study or not. And then, on Day -1, eligib...

Eligibility Criteria

Inclusion

  • Men and Women between 20 and 80 years of age
  • History of laparoscopic surgery
  • American Society of Anesthesiology Physical Class 1-3
  • Ability and willingness to provide informed consent

Exclusion

  • History of hypersensitivity or allergy to opioid, NSAIDs, or Acetaminophen
  • Chronic preoperative opioid use
  • Severe comorbidity which is able to interfere pain assessment
  • Ostomy surgery of intestine within the past 8 weeks
  • Pregnant or breastfeeding

Key Trial Info

Start Date :

March 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 31 2019

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT03854851

Start Date

March 1 2019

End Date

October 31 2019

Last Update

February 26 2019

Active Locations (1)

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China Medical University & Hospital

Taichung, Taiwan, 404