Status:
COMPLETED
The Effect of Childhood Dyslipidemia on Endothelial and Renal Function
Lead Sponsor:
University of Ioannina
Collaborating Sponsors:
University Hospital, Ioannina
Conditions:
Dyslipidemias
Children, Only
Eligibility:
All Genders
7-17 years
Brief Summary
The aim of the study is to assess if abnormal lipid levels in childhood could cause early damage of the inner layer of the vessels, the endothelium. Dysfunction of the endothelium is the first event i...
Detailed Description
In children recruited in the study, family history of dyslipidemia or premature cardiovascular disease will be recorded. Furthermore, anthropometric and clinical characteristics will be noted and lipi...
Eligibility Criteria
Inclusion
- Children and adolescents aged 7 to 17 years
- Dyslipidemia (serum levels of LDL-cholesterol ≥95th percentile or serum levels of triglycerides ≥95th percentile or serum levels of HDL-cholesterol ≤5th percentile for age and sex)
Exclusion
- History of renal disease
- Dyslipidemia caused by nephrotic syndrome or chronic kidney disease
- Chronic use of medication
- Acute or chronic inflammatory process
Key Trial Info
Start Date :
April 3 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 3 2020
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT03856476
Start Date
April 3 2017
End Date
April 3 2020
Last Update
November 3 2020
Active Locations (1)
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1
University of Ioannina
Ioannina, Greece, 45500