Status:
WITHDRAWN
Opioids and Smoking Cessation
Lead Sponsor:
University of Houston
Conditions:
Smoking
Smoking Cessation
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
The selection hypothesis of smoking prevalence posits that smokers who are not able to quit successfully are "burdened" by specific characteristics that make it more challenging to quit1. For example,...
Detailed Description
B. BACKGROUND/SIGNIFICANCE B.1. Tobacco Smoking. Smoking is responsible for over 40% of premature deaths and disability in the US1, and has been estimated to cost $96 billion in direct medical expense...
Eligibility Criteria
Inclusion
- 1\. 18-65 years of age. 2. Daily smoker (≥ 10 cigarettes per day for at least one year), biochemically confirmed via Carbon Monoxide \[CO\] analysis at least 8 ppm.
- 3\. Motivation to quit smoking (≥ 5 on a 0-10 scale) 4. Interested in making a serious quit attempt in the next month 5. Not have decreased number of cigarettes by more than half in the past 6 months 6. Own a smartphone (for EMA) 7. Report of current (past 30-day) opioid use (opioid misuse group) 8. Verification of opioid use by positive urine toxicology screen \& Positive Aberrant Drug Behavior Index (opioid misuse group)
- PDUQ \> 11, +POTQ, +urine toxicology screen
Exclusion
- 1\. Current use of psychotropic medication. 2. Current use of nicotine replacement therapy, Zyban, or Chantix (or intention to use).
- 3\. Use of other tobacco products, including e-cigarettes. 4. Current treatment for opioid misuse, including methadone, buprenorphine, or naltrexone.
- 5\. Current diagnosis of Opioid Use Disorder. 6. Pregnancy (by self-report) 7. Limited mental capacity or inability to provide informed consent 8. Current suicidality (by structured clinical interview) 9. Lifetime or current psychosis
Key Trial Info
Start Date :
December 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2023
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT03857139
Start Date
December 1 2020
End Date
January 1 2023
Last Update
May 20 2022
Active Locations (1)
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1
Anxiety and Health Research Laboratory
Houston, Texas, United States, 77204