Status:
COMPLETED
a-Klotho in Relation to Calcification in the Coronary Arteries and Aortic Valve in Patients With Chronic Kidney Disease
Lead Sponsor:
Royal Brompton & Harefield NHS Foundation Trust
Collaborating Sponsors:
AHEPA University Hospital
Conditions:
Vascular Calcification
Chronic Kidney Diseases
Eligibility:
All Genders
18+ years
Brief Summary
To define the correlation of the levels of a-Klotho with the severity of vascular calcification in the coronary arteries and aortic valve.
Detailed Description
Vascular calcification is a well-defined risk factor for cardiovascular disease and a-Klotho has been suggested to be an implicating factor in the process of vascular calcification, particularly in pa...
Eligibility Criteria
Inclusion
- Patients with stable chronic kidney disease stage V under intermittent hemodialysis and, patients with stable chronic kidney disease stage III
Exclusion
- Active cancer
- Inflammatory or granulomatous disease
- Primary hyperparathyroidism
- Patients unable to provide informed consent
Key Trial Info
Start Date :
January 15 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2018
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03858413
Start Date
January 15 2016
End Date
December 31 2018
Last Update
February 28 2019
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