Status:
COMPLETED
Hemodynamics During Induction of General Anesthesia With High and Low Propofol Dose.
Lead Sponsor:
Helse Fonna
Conditions:
Hemodynamics Instability
Anesthesia, General
Eligibility:
FEMALE
18-50 years
Phase:
PHASE4
Brief Summary
The study objective is to examine if a high propofol dose is non-inferior to a low dose in respect to hemodynamic stability in healthy patients during induction of general anesthesia with propofol and...
Detailed Description
Typically, one or more adjuvant medications are administered to supplement induction of general anesthesia. When combining anesthetic drugs, the hypnotic effects are often synergistic. Propofol is ass...
Eligibility Criteria
Inclusion
- Healthy women
- Age 18-50 years
- Gynecological procedures
- General anesthesia
Exclusion
- Pre-existing hypertension
- Diabetes for several years
- Ischemic heart disease
- Cerebrovascular disease
- Heart valve disease
- Verified cardiac arrhythmia
- Anaemia
- Kidney or hepatic disease
- Hypersensitivity for soya, eggs or peanuts
- Pregnancy
- Poor health state
- Illicit substance use
- BMI \<20 or \>35 kg/m2
- SBP \>150 mmHg
- HR \>100 beats/min
Key Trial Info
Start Date :
September 3 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 31 2020
Estimated Enrollment :
68 Patients enrolled
Trial Details
Trial ID
NCT03861364
Start Date
September 3 2019
End Date
May 31 2020
Last Update
June 17 2020
Active Locations (1)
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1
Kirurgisk Klinikk-Anestesi
Haugesund, Rogaland, Norway, 5504