Status:

TERMINATED

REMAP Trial for Optimizing Surgical Outcomes at UPMC

Lead Sponsor:

Matthew Neal MD

Collaborating Sponsors:

University of Pittsburgh Medical Center

Berry Consultants

Conditions:

Aging

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The purpose of this project is to determine the effect of various interventions to improve patient outcome as defined by hospital free days at day 90 for adult patients undergoing elective surgery. Wi...

Eligibility Criteria

Inclusion

  • UPMC REMAP
  • Adult patient evaluated pre-operatively for elective surgery at UPMC
  • Minimum lead time before surgery to provide domain specific intervention (range 7-180 days pre-operatively)
  • Age greater to or equal to 18 years of age

Exclusion

  • Death is deemed to be imminent or inevitable
  • Emergency surgical procedure without suitable lead-in time
  • Previous participation in this REMAP within the last 90 days, flagged by elective or emergency surgical encounter at UPMC in the past 90 days
  • SPRY Domain
  • Inclusion Criteria:
  • Age \>= 60 years
  • Age \< 60 but evidence of comorbidity risk as represented by a Charlson Comorbidity Index of \> 2 in 12 months prior to enrollment
  • Able to take an oral medication in non-crushable pill form
  • Women must be post-menopausal, which is defined as not having a menstrual period within the last 12 months

Key Trial Info

Start Date :

April 15 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 23 2022

Estimated Enrollment :

302 Patients enrolled

Trial Details

Trial ID

NCT03861767

Start Date

April 15 2019

End Date

September 23 2022

Last Update

June 18 2024

Active Locations (1)

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1

UPMC

Pittsburgh, Pennsylvania, United States, 15213