Status:
RECRUITING
Cognition and NeuroImaging in neuroDegenerative Disorders (CogNID)
Lead Sponsor:
Nottingham University Hospitals NHS Trust
Conditions:
Dementia (Diagnosis)
Eligibility:
All Genders
18+ years
Brief Summary
This prospective study aims: 1. to compare cognitive performance in different clinical groups of participants with mild cognitive impairment (MCI) or mild dementia \[Alzheimer's Disease (AD), Vascula...
Detailed Description
The imaging arm of the study include: 1. to demonstrate differences in brain iron levels between different dementia syndromes and healthy volunteers using ultra high-field MRI, quantitative susceptib...
Eligibility Criteria
Inclusion
- Ability to give informed consent.
- Either pathological, genetic or imaging biomarker evidence to suggest Fronto-temporal Lobar Degeneration, Alzheimer's Disease or Vascular Cognitive Impairment, or defined clinical diagnoses.
Exclusion
- Lack of mental capacity to consent to study involvement.
- Not speaking English before age 5 years.
- Learning disability.
- MRI contraindications
Key Trial Info
Start Date :
December 12 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2025
Estimated Enrollment :
125 Patients enrolled
Trial Details
Trial ID
NCT03861884
Start Date
December 12 2018
End Date
March 1 2025
Last Update
March 21 2024
Active Locations (2)
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1
Nottinghamshire Healthcare NHS Foundation Trust
Nottingham, Easat Midland, United Kingdom, NG7 2TU
2
Nottingham University Hospitals NHS Trust
Nottingham, East Midland, United Kingdom, NG7 2UH