Status:

UNKNOWN

Re-evaluation of Donor-specific Anti-HLA Alloantibodies Immunoassay After Organ Transplantation, From Antigen Level to Epitope Level

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Conditions:

Organ Transplantation

Eligibility:

All Genders

7+ years

Brief Summary

Transplantation is the only treatment for end-stage organ dysfunction, with dialysis for the kidney. However, donor / recipient (D / R) tissue incompatibility accounts for the majority of long-term gr...

Eligibility Criteria

Inclusion

  • patients (adults and children)
  • patients recipients in France from 2008 to 2015 of a first kidney transplant / heart / lung / liver donor living or deceased, non-immunized anti-HLA before the transplant
  • patients having preserved their graft \> 2 years
  • having agreed to the use for research purposes in transplantation of the remains of the DNA and serum samples taken as part of the care of which the remains are available

Exclusion

  • no inclusion if one of the inclusion criteria is not met

Key Trial Info

Start Date :

May 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 1 2025

Estimated Enrollment :

20000 Patients enrolled

Trial Details

Trial ID

NCT03861962

Start Date

May 1 2019

End Date

May 1 2025

Last Update

April 29 2019

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Re-evaluation of Donor-specific Anti-HLA Alloantibodies Immunoassay After Organ Transplantation, From Antigen Level to Epitope Level | DecenTrialz