Status:

COMPLETED

Myocardial Perfusion Imaging in Liver Transplantation Candidates

Lead Sponsor:

University Hospital Birmingham NHS Foundation Trust

Conditions:

Myocardial Perfusion Imaging

Liver Failure

Eligibility:

All Genders

18+ years

Brief Summary

The optimal screening strategy for assessment of coronary artery disease in patients with end-stage liver disease (ESLD) is unclear. Although consensus based guidelines support noninvasive stress test...

Detailed Description

Controversy over whether SPECT imaging offers clinical utility in ESLD has been fuelled by conflicting reports on its accuracy to diagnose CAD in this setting. Moreover, there are no studies examining...

Eligibility Criteria

Inclusion

  • • Liver transplantation candidates with one or more of the following:
  • inability to perform \>4 METs by history
  • insulin-treated diabetes mellitus
  • serum creatinine \>152μmol/l
  • history of MI, PCI or CABG
  • stable angina
  • cerebrovascular disease
  • peripheral vascular disease

Exclusion

  • Age \< 18 years
  • Pregnancy
  • Contraindication to liver transplantation

Key Trial Info

Start Date :

September 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2019

Estimated Enrollment :

403 Patients enrolled

Trial Details

Trial ID

NCT03864497

Start Date

September 1 2007

End Date

June 1 2019

Last Update

June 19 2019

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