Status:
UNKNOWN
Unravelling the Alteration of Brain Structure and Function in Parkinson´s Disease With Ultra-high Field MRI
Lead Sponsor:
Danish Research Centre for Magnetic Resonance
Collaborating Sponsors:
Bispebjerg Hospital
Conditions:
Parkinson Disease
Eligibility:
All Genders
18-100 years
Brief Summary
Parkinson's Disease (PD) is a neurodegenerative disease characterized by a range of disabling motor- and non-motor symptoms caused by a loss of neurons in neuromodulatory brainstem nuclei. Typical mot...
Detailed Description
BACKGROUND Parkinson's disease (PD) is a multi-system neurodegenerative disease affecting a subset of vulnerable cells in various brain structures, including brain stem nuclei. Selective degeneration ...
Eligibility Criteria
Inclusion
- Parkinson's Disease (PD) group
- Inclusion criteria:
- Aged 18 or more.
- Clinically established or probable PD according to the Movement Disorder Society Clinical Diagnostic Criteria for Parkinson's Disease
- Signed informed consent
- Exclusion criteria:
- Pregnancy or breastfeeding
- History of other neurologic or psychiatric disease
- Pacemaker or other implanted electronic devices
- Claustrophobia
- Healthy participants age- and sex-matched to the PD group:
- Inclusion criteria:
- Age- and sex-matched to PD group (aged 18 or more)
- Signed informed consent
- Exclusion criteria:
- Pregnancy or breastfeeding
- History of neurologic or psychiatric disease
- Pacemaker or other implanted electronic devices
- Claustrophobia
Exclusion
Key Trial Info
Start Date :
September 19 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2024
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT03866044
Start Date
September 19 2018
End Date
December 1 2024
Last Update
May 18 2022
Active Locations (2)
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1
Department of Neurology, Copenhagen University Hospital Bispebjerg
Copenhagen, Denmark, 2400
2
Danish Research Centre For Magnetic Resonance, Copenhagen University Hospital Hvidovre
Hvidovre, Denmark, 2650