Status:
COMPLETED
The Natural History of Injury-Related Disuse Osteopenia
Lead Sponsor:
Milton S. Hershey Medical Center
Conditions:
Osteopenia
Eligibility:
All Genders
18-70 years
Brief Summary
Determine the severity and time course (natural history) of disuse osteopenia that occurs in the lower extremity(ies) and lumbar spine of patients sustaining lower extremity injuries that require the ...
Detailed Description
It is well documented that restricted weight bearing even for relatively short periods (12 weeks) associated with the surgical treatment of peri-articular injuries of the lower extremity (ie acetabulu...
Eligibility Criteria
Inclusion
- Age 18-70 at time of injury
- Previously normal community ambulator (without ambulatory aid) prior to injury
Exclusion
- Presence of a total or hemi hip prosthesis in the injured extremity
- Presence of lumbar fusion L1-L4
- Previous ipsilateral lower extremity trauma
- History of medical treatment for known osteoporosis (Calcium and Vitamin D supplementation alone is NOT an exclusion criteria)
- Ambulatory dysfunction prior to injury
- Inability to cooperate with DXA scanning
- Head injury on admission requiring invasive monitoring or treatment
- Inability to adhere to weight bearing restrictions
- Inability to provide consent
- Non English speaking
- Pregnancy
Key Trial Info
Start Date :
May 31 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 10 2020
Estimated Enrollment :
51 Patients enrolled
Trial Details
Trial ID
NCT03868085
Start Date
May 31 2017
End Date
December 10 2020
Last Update
February 28 2023
Active Locations (1)
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1
Milton S. Hershey Medical Center
Hershey, Pennsylvania, United States, 17033